Hotels in Rochester

Cozy & Convenient Rochester Retreat! Just minutes from the world-renowned Mayo Clinic and vibrant... downtown, this charming 2-bedroom, 2-bathroom home offers the perfect blend of comfort, convenience, and character. Whether you're here for medical visits, family time, or remote work, this Rochester retreat has everything you need - a restful, well-appointed space for relaxation or work, with fast access to Mayo Clinic, local attractions, and dining.
Space & Comfort
Bedrooms: Two well-appointed bedrooms featuring fresh, quality linens—ideal for families, small groups, or business travelers.
Living Areas: Cozy main-floor living room with a smart TV and seating for everyone, alongside a spacious lower-level family room—great for gatherings, streaming, or kids’ playtime.
Kitchen: Fully stocked modern kitchen with stainless steel appliances, ample cookware, and a Keurig coffee maker for your morning brew.
Bathrooms: Main-floor full bath with tub, plus an updated lower-level bath with a walk-in shower—both sparkling clean.
Amenities
High-speed Wi‑Fi
Central air conditioning, forced‑air heating, and new flooring throughout ensure year‑round comfort.
Laundry essentials: washer and dryer included.
Free off‑street parking— driveway included.
Outdoor enjoyment: private (fully fenced!) spacious yard with patio seating—ideal for furry friends or unwinding after a long day
Location Highlights
Proximity: Just 5–10 minutes to downtown and Mayo Clinic—great for appointments, conferences, or exploring the city
Walkability: Close to quiet, friendly neighborhoods with quick access to parks, grocery stores, coffee shops, and dining.
Connectivity: Located near biking trails that connect you to Silver Lake and the scenic city park networkAbout pets:Pets allowed: limit 2 total.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed. More...

Escape to the heart of Rochester, Minnesota in this charming 3-bedroom vacation home. Nestled just a... 10 minute walk from Mayo Clinic and a 16-minute walk from the Mayo Civic Center, you'll be perfectly positioned to explore all that this vibrant city has to offer. After a day of discovering the nearby Rochester Recreation Center, just 4 minutes away by car, return to your cozy home-away-from-home and enjoy the comforts of free WiFi and a convenient washer and dryer. Wake up refreshed each morning, thanks to the essential amenities provided, including a bathroom, towels, basic soaps, a hair dryer, an iron and board, and climate-controlled air conditioning and heating. With all the comforts of home and the excitement of Rochester at your fingertips, this vacation rental is the perfect base for your next getaway.About pets:No pets allowed.About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 3:30 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed. More...

Enjoy your stay at this 3 bedroom and 1 bath upper level home.
I look forward to hosting you, feel... free to call or text with questions to help book. We have multiple short term rentals to fit your needs and budget!!
Fully furnished with everything you should need to make your stay comfortable. Enjoy relaxing inside this clean comfortable home or take advantage of the walking trails. The home is located just 2 blocks from the Mayo Campus with off street garage parking.
The Upper unit is a 2 level, 3 bedroom/1 bath. The master and second bedroom are furnished with Queen beds, nightstands, lamps, and full mirrors. The 3rd bedroom is furnished with a single bed, desk, lamp, and mirror. The kitchen is fully furnished for all of your cooking and baking needs. High speed wifi, cable, smart tv, Keurig/coffee, dishwasher, Washer/dryer, and water softener. Enjoy making a cup of coffee at the mini bar. Relax in the spacious living room and dining room area. There is a walk out porch from the kitchen and beautiful fenced backyard. Off street parking in a garage.
This home is professionally cleaned. It meets and exceeds all covid clean restrictions set by vrbo. Many bathroom and kitchen essentials are provided.About pets:No pets allowed.About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed. More...

TownePlace Suites Rochester Mayo Clinic Area is a downtown Rochester, MN, hotel where you can... balance work and life as you like with the comfort, flexibility and affordability you require. Relax and feel at home in our Rochester, MN extended-stay hotel with a fully equipped kitchen and high-speed Internet access. Hotel guests enjoy free door-to-door shuttle service to the Mayo Clinic St. Mary's Campus, Mayo Clinic Methodist Campus, Mayo Civic and Convention Center, Dan Abraham Healthy Living Center and other nearby restaurants, attractions and businesses within two miles. Enjoy your favorite coffee, beer, or wine in Spyhouse Coffee Roasters on-site. Take a walk to the Zumbro River only six blocks away. Experience the beauty of the Silver Lake area only one mile away. Get a robust fitness workout in our oversized Premium Matrix Fitness Center. Be sure to start your day in Rochester with a free hot breakfast daily including all your favorites like waffles, eggs, sausage and more! More...

Brand new furnishings new appliances!
Enjoy easy access to everything from this perfectly located... condo. 2 miles from Mayo and St Mary's, 3 miles to Target and Aldi and on the bus line! There is a fitness area with sauna and dressing area, indoor and outdoor pools, BBQ and picnic area.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Adults only.About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 25.About events:No events allowed. More...

Two bedroom apartment in a duplex house main floor. Located in historic SW ,only two blocks away... from Mayo clinic downtown campus and six blocks away from St Mary hospital!
>Free Parking
>Laundry in Unit
>Unlimited On-Demand Movies/TV, About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed. More...

This comfortable home has three bedrooms with one king size bed, one full and one twin bed. Little... Blue, as we affectionally call it, has been thoughtfully designed and renovated for visitors to Mayo It is nestled in the charming & quiet Historic Southwest neighborhood. Steps away from Soilder's Field Park which has a playground, walking paths and a dog park. Conveniently located close to downtown, restaurants, grocery stores and coffee shops. This newly remodeled kitchen has all new stainless steel appliances with the latest kitchen electrics and modern bakeware that you could desire. Super Fast WiFi and Netflix.About pets:Pets allowed: dogs less than 50 lbs per pet (limit 2 pets total).Hello. We do allow well behaved pets..About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About customRules:This property pet friendly, however NO Cats!
Owner is very allergic to cats..About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 24.About events:No events allowed. More...

The Residence Inn Rochester Mayo Clinic Area is conveniently located downtown Rochester, MN within... walking distance to the world-famous Mayo Clinic. Enjoy our newly renovated well-appointed 1 or 2 bedroom suite with a sofa bed, kitchen with microwave, full-size fridge, stovetop, dishwasher, and cookware. Complimentary amenities include a hot breakfast each morning, Wi-Fi access, a 24-hour fitness center, and a rooftop patio. Host up to 20 people for a business meeting in the Silver Lake Meeting room. The Residence Inn Rochester Mayo Clinic Area is 9 miles from the Rochester International Airport and provides access to Mayo Clinic via a indoor pedestrian walkway. Our hotel in downtown Rochester, MN is centrally located to St. Mary’s Hospital and Methodist Hospital. Please be aware there is on-going Mayo construction next to us, which may cause noise related concerns during your stay. More...

The 5th Avenue Inn & Suites is an ideal spot for travelers wanting to discover the city. The 5th Avenue Inn & Suites offers a pleasant stay in Rochester for those traveling for business or leisure.

Come join us for a fantastic stay in a well-appointed 3-bedroom, 1 bath, UPPER-LEVEL DUPLEX 5... minutes to Mayo Clinic? This unit is recently remodeled, beautifully furnished and very convenient.
You will find everything you might need to recover from a surgery or to feel at home while seeking treatment.
The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pack-n-Play and highchair are available.
Dogs are welcome with a charge of $50/dog.
•Recently remodeled
•Beautifully furnished & decorated
•Fully equipped kitchen
•Sleeps six
•Child friendly with toys, books & bunkbed
•Pack-n-play and highchair included
•5 minutes to Mayo Clinic
•Bus stop and multiple restaurants 1 minute away
•On-site free SHARED washer & dryer (accessible via a rear entrance to the property.)
•The rear access to the property includes a deck with table, chairs and a BBQ grill during summer months.
•On-site free parking for 2 vehicles
•Check in at 4pm
•Check out at 10am
•"A superbly appointed and newly renovated home, would definitely stay here again!"
The kitchen contains everything needed for food preparation including a microwave, electric stove/oven, both a Keurig coffee maker and a traditional electric coffee pot, a blender, a full set of pots and pans, a dishwasher to make clean-up more convenient and a selection of common spices for cooking, as well as flour, sugar, and cooking oil. Bring a bag of groceries and you are set to live in your home-away-from-home as long as you need to!
There are BPA-free children's dishes in addition to a full set of traditional dishware. We highly recommend when you arrive that you take a look in the cabinets and under the stove, so you familiarize yourself with the appliances, dishes and utensils.
Relax in the living room with our gas fireplace TV stand, comfortable sofa and--the unassuming star of the show--the heated massage recliner. Those guests recovering from medical procedures find the lift function of this chair a big help.
One of the bedrooms includes a dedicated workspace, including a desk, office task chair and a lamp. Two bedrooms include hybrid queen mattresses, (with foam mattress toppers), blackout curtains, 100% cotton sheets, and extra bedding if you like to sleep toasty warm.
The third bedroom features a camping theme. It was carefully designed to make a child's stay a memorable one, complete with a tent, a bunkbed with forest animal sleeping bags, and thoughtfully chosen creative toys and books designed to delight your little ones. (Traditional bedding is also on site for older guests using the "bunkhouse.")
The house has central heat and window air conditioners plus a fan if you like white noise when you sleep.
Cleaning supplies you may want during your stay are stored in the living room and hallway closets as well as under the kitchen sink.About pets:Pets allowed: dogs less than 50 lbs per pet (limit one pet total).Pet fee is $50 per pet. Must be crated if alone..About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.Pack and play and highchair included..About customRules:Smoking inside the property will result in a $250 charge per day of the reservation. Guests agree to abide by this policy by booking the property..About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:Events allowed: family gatherings and birthday parties.Maximum event attendees: 6. More...

Brentwood Inn & Suites is centrally located in Rochester, a 4-minute walk from Mayo Clinic and 8 minutes by foot from University of Minnesota-Rochester. This hotel is 0.5 mi (0.8 km) from Mayo Civic Center and 0.8 mi (1.3 km) from Mayo Clinic Hospital - Saint Marys Campus.

Come join us for a fantastic stay in a well-appointed 2-bedroom 1 bath LOWER-LEVEL DUPLEX 5 minutes... to Mayo Clinic? This unit is recently remodeled, beautifully furnished and very convenient.
You will find everything you might need to recover from a surgery or to feel at home while seeking treatment.
The house is child friendly with a nice selection of toys and books to keep the little ones occupied. Pack-n-Play and highchair are available.
A maximum of 2 DOGS are welcome with a charge of $50/DOG.
There is in unit access (via a lockable door) to a SHARED LAUNDRY ROOM.
On-site free parking for 2 vehicles
Check in at 4pm
Check out at 10amAbout pets:Pets allowed: dogs less than 20 lbs per pet (limit one pet total).About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About customRules:Smoking in the property will result in a $250 additional cleaning fee for each day of the reservation. Guests agree to this policy by booking..About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:Events allowed: family gatherings and birthday parties.Maximum event attendees: 7. More...

Our modern and spacious guestrooms and suites are fitted with HDTVs and kitchenettes perfect for extended stays. Stay connected with free Wi-Fi and enjoy convenient parking

Discover the perfect blend of comfort and convenience in our spacious 2-bed, 1-bath main level... apartment. Nestled in a quiet residential neighborhood, this inviting space is a quick walk, bike ride, or drive from downtown Rochester. The fully equipped kitchen invites you to prepare home-cooked meals, while high-speed fiber optic Wi-Fi keeps you connected. Don’t forget the convenience of garage parking - a secure spot for your vehicle, shielding it from the elements. On-site laundry as well!
The two bedrooms, one with a queen-sized bed and the other with a full-sized bed, each come with sound machines and wireless chargers. There is closet space and a dresser in each bedroom to ensure you have enough room for your clothing and personal items.
The deck off the second bedroom allows for refreshing, outdoor relaxation.
The living room includes comfortable couch, oversized chair, and smart tv, allowing you to utilize all your streaming services. The perfect place to relax and unwind.
There is a coffee nook with two chairs, small table, and lamp - the perfect cozy spot to do a bit of reading.
A full kitchen, including complete place settings, cooking utensils, dishwasher, microwave, and oven/stovetop allows you to have meals just like you're at home.
On site laundry means you don't have to worry about finding a laundromat during your stay.About pets:No pets allowed.About children:Children allowed: ages 0-17.About smoking:Smoking is not permitted.About events:No events allowed. More...

This charming and spacious home in downtown Rochester is perfect for a short or extended stay. It... has everything on the main floor for a couple, but lots of space to entertain the whole family! The house has new kitchen appliances, stocked kitchen, washer and dryer, one king and two queen beds with comfortable bedding, and a large smart tv with Roku. You're close to Mayo Clinic by either walking or a quick drive.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed. More...

Your family will be close to everything when you stay at this centrally-located single family home... Goose Egg children’s park with tennis courts across the street. Less than 10 minutes walking distance away from Downtown Rochester, And Mayo Clinic facilities. Relax on the front porch while looking at Goose Egg park or go to the fenced in back yard to enjoy the deck and fire pit. Parking out front on street and 2 spaces out back by the garage. Full kitchen and laundry located down stairs.About pets:Pets allowed: limit 4 total.Will supply scooper to clean up after dogs..About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 20.About events:No events allowed. More...

Thank you for choosing our AmericInn by Wyndham Rochester Near Mayo Clinic hotel.

Apartment-style rooms feature the Hyatt Grand beds, state-of-the-art media and work center with a... high-definition 42-inch flat panel HDTV that easily integrates with laptops, a comfortable cozy corner L-shaped sofa-sleeper, wet-dry bar and bathroom vanity with granite countertops. Enjoy comp wireless high-speed internet and comp a.m. Kitchen Skillet, with hot breakfast items, fresh fruit, oatmeal and plenty more to choose from. Parking Fee 15 USD daily. More...

In Lowertown-A quaint cottage with modern updates is your home away from home! Fully furnished and a... well stocked kitchen make it a wonderful place for overnight stays or longer term rentals. Beautiful patio provides an urban sanctuary at the end of a long day. Close proximity to Mayo Clinic-downtown restaurants, grocery stores and shopping are within walking distance. Two blocks in either direction puts you on the trail system. Public transit 1 ½ blocks away and a laundromat is ½ block away.
This home provides everything you need for a stay in Rochester: fully furnished, all kitchen essentials and if there is something you need just ask and we can probably provide it! This home's two bedrooms sleep 4 people comfortably. There is also a “bonus” room with a queen size bed that can be used as a third bedroom . (Additional guests over 4 are $10 per night) During the summer season we are happy to have you help yourself to what is growing in the backyard garden. We typically have asparagus, rhubarb, onions, tomatoes and peppers.
You will have access to the 1 1/2 story home, the yard and patio. There is free street parking. The basement is private owner area. We live next door so can be available when needed. We are happy to share our knowledge of the Rochester area and of course our favorite restaurants!
We LOVE our neighborhood as it provides us with the sustainable lifestyle that is important to us. We can walk or bike to most everything we need within 10 minutes. We try to be as environmentally conscious as possible so don't use any pesticides, insecticides or harsh chemicals inside or out. In 2021 the newest additions to our urban homestead were CeCe, Tiffany and Sunshine-three laying hens that provide us with the eggs we need. The home we live in (next door) has been featured in several articles in and around Rochester as we strive to achieve as close to net-zero energy use as possible. If you are interested in a tour let us know!
This neighborhood is in the perfect setting; close to downtown but away from the main busy streets. Goose Egg Park (named for the shape ;-) is 2 blocks away and Silver Lake Park is 3 blocks away-so easy to take a little stroll on the paths or around the lake. Nearby in the Cook Park area of Lowertown are Garden Party Books, Pop's Art Theater and Wear Local. 125 Live is one of the newest offerings in our neighborhood with classes, art shows and many other events happening. Rochester Farmer's Market operates year round at Graham Park on Saturday mornings and in the summer Wednesdays are added.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 3-17.Open stairway to 2nd floor
Step down to kitchen.About customRules:Photo ID required at time of payment.FYI: 15.125% required MN, Rochester Sales Tax will be included in your price. All STR, hotels are required to charge this in addition to nightly rate.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 21.About events:No events allowed. More...